Dr. C.G Pramila

More than 28 years' experience as Radiation Oncologist with significant accomplishments in the management of solid tumors and teaching medical students on basics of oncology and advanced radiotherapy techniques.

OBJECTIVE

To achieve heights of excellence in the field of Radiation Oncology, through dedicated patient care, accurate execution of treatment options, perseverance to learn state of the art technologies, conducting research and studying better ways for the management of cancer; and above all through humanitarian considerations.

PRESENT POSITION

PREVIOUS POSITION

Areas of Interest

• Women’s health care – Breast and Gynecologic malignancies
• Head and neck and Lung cancers
• Palliative Oncology
• Preventive Oncology

CURRENT RESEARCH PROJECTS

• Pattern of disease profile in triple negative breast cancer
• Dose to parotid and resultant quality of life assessment
• Dose to structures of DARS and the relation to swallowing in patients on IMRT – A prospective study
• Radiation pneumonitis in breast irradiation, a collaborative study with MIE university, Japan
• Hypofractionated radiation to chest wall using single enface electron ports
• Androgen receptor positivity in triple negative breast cancer and the significance
• Dysphagia aspiration related structures and the effects of radiation – IMRT vs 3DCRT
• Late solitary lung metastasis in endometrial adenocarcinoma
• Primary vaginal carcinoma – prognostic factors and relation to treatment outcomes
• Primary oesophageal carcinoma and effects of ILRT
• Primary oesophageal carcinoma and the results of tri-modality treatment
• Outcome analysis in Adenocarcinoma of Stomach, a Single Institute, Five-year Retrospective analysis

TECHNICAL EXPERIENCE

• Planning, contouring and plan evaluation in Eclipse and in Focal planning system.
• Planning in Varian Rapid Arc system, and in Electa.
• Simulator planning and verification.
• Computerized dosimetric planning systems.
• Treatment planning and execution using linear accelerators and tele-cobalt units.
• Treatment planning with IGRT, IMRT, 3DCRT techniques
• Active Breath Co-coordinator (ABC) modes in treatment planning
• Exposures to Stereo-tactic radio-surgery (SRS) and stereo-tactic radiotherapy (SRT).
• Exposure to SBRT in lung and liver lesions
• Intra-cavitary brachytherapy using high dose rate and low dose rate applicators.
• Concomitant chemo-radiation for managing various malignancies.
• Use of chemotherapy drugs in the adjuvant and palliative management of malignancies.

CLINICAL EXPERIENCE

• Management of solid tumors in various anatomical locations, achieving good results in curative and palliative situations.
• Involved in the palliative care management of cancer patients.
• Holistic approach towards the patient and relatives including medical, social, psychological and financial aspects.
• Involved in hospice care.

RESEARCH EXPERIENCE

• Swallowing structures and the relation of dose of radiation and swallowing status
• Use of prosthesis in external auditory canal and outcomes in radiotherapy to head and neck
• Androgen receptor positivity in triple negative breast cancer and its prognostic value.
• Hypofractionated radiation to chest wall and the use of single enface electron fields.
• Study of aromatase inhibitor induced loss of bone mineral density being corrected by the use of bis­phosphonates.
• Retrospective analysis of Wilm’s tumor

TEACHING - LEARNING EXPERIENCE

• Teaching post-graduate students since 2011
• Oral and poster presentations at various national and international conferences
• Active participation in various conferences and CMEs, abroad and within the country.
• Teaching undergraduate medical students since 1995.
• Teaching nursing and para-medical staff since 2004.
• Active participation in cancer awareness programs.
• Addressing the public on early detection and treatment of cancer.

REVIEWER

• Indian Journal of Cancer
• Current Oncology
• Archives of Medical Research
• PLOS ONE International Journal
• European Journal of Oncology
• Journal of Clinical and Diagnostic Research

OTHERS

Instrumental in achieving collaboration and signing a MOU with “MIE University Graduate School of Medicine”, at Tsu, Japan in April, 2011, and was involved in the student exchange program between the two universities since 2011 - 2017

SOCIAL COMMITMENTS

Attached with Pratheeksha Palliative Care Center, Koottanad - Helping in the care of patients – Since 2015

PUBLICATIONS

1. Priyanka Manchenahalli Venkatesh Prasad, Prameela G Chelakkot, Geetha S Narayan. Intramuscular injection of human placental extract versus conventional symptomatic approaches in radiation-induced oral mucositis, in patients with head and neck cancers, on definitive chemoradiotherapy – A ray of hope? Journal of Cancer Research and Therapeutics. 2024, 20 (3): 776-781
2. Sandya C Jayasankaran, Prameela G Chelakkot, Aarathi Suresh, Smitha N V, Krishnakumar Thankappan, Subramanya Iyer, Srikanth Moorthy. Depth of Invasion in Squamous Cell Carcinoma of Buccal Mucosa: Is Magnetic Resonance Imaging a Good Predictor of Pathological Findings? Gulf Journal of Oncology. 2022, 39: 39-46
3. Michelle Aline Antony and Prameela G Chelakkot. Retrospective study of the clinicopathological characteristics of adult granulosa cell tumour of the ovary at a tertiary care centre. Indian Journal of Gynecologic Oncology. 2020, 18:40
4. Jayasankaran SC, Prameela G Chelakkot, Prabhash Prabhakaran, Resmi Sekhar. Role of diffusion weighted magnetic resonance imaging in the evaluation of ovarian tumors. Indian Journal of Gynecologic Oncology. 2019, 17:64 (First online: 24 July 2019)
5. Prameela G Chelakkot, Rahul Ravind, Sruthi K, Durgapoorna Menon. Treatment in resectable non‑metastatic adenocarcinoma of stomach: Changing paradigms. Indian Journal of Cancer 2019; 56 (1) 74-78.
6. Chelakkot G Prameela, Ravind, Rahul, K, Sruthi. Non-thyroidal metastatic lesion in thyroid: A missed diagnosis and a lesson learnt. Journal of Cancer Research and Therapeutics 2019; 15 (3) 665-668. (DOI: 10.4103/jcrt.JCRT_1043_16)
7. Chelakkot G. Prameela, Rahul Ravind, K. Sruthi, Haridas M. Nair, M Dinesh. Surgical resection of solitary distant metastasis from locoregionally controlled, advanced hypopharyngeal malignancy: A ray of hope. Journal of Cancer Research and Therapeutics. 2018;14: 697-700. (DOI: 10.4103/0973-1482.172124)
8. Sruthi K, Prameela G Chelakkot, M Dinesh et al. Single fraction radiation: A promising adjuvant therapy to prevent keloid recurrence. Journal of Cancer Research and Therapeutics. 2018;14: 1251-1255.
9. Jayasankaran SC, Prameela G Chelakkot, Karippaliyil M, Thankappan K, Iyer S, Moorthy S. Magnetic resonance imaging: A predictor of pathological tumor dimensions in carcinoma of anterior two‑thirds of tongue ‑ A prospective evaluation. Indian Journal of Cancer. 2017; 54:508-513 (DOI: 10.4103/ijc.IJC_319_17)
10. Jayasankaran SC, Prameela G Chelakkot, Thankappan K, Iyer S, Moorthy S. Paralingual and sublingual space invasion in magnetic resonance imaging of squamous cell carcinoma of anterior two‑thirds of tongue: Is there a prognostic significance? A prospective evaluation. Indian Journal of Cancer. 2017; 54 (2): 442—446 (DOI: 10.4103/ijc.IJC_318_17)
11. Durgapoorna Menon, Prameela G Chelakkot, Devika Sunil, Ashwini Lakshmaiyah. A cross sectional review of patient information available in the world wide web on cyberknife: fallacies and pitfalls. Supportive Care in Cancer 2017
12. Narayan R Subramaniam, Vijay Kumar Srinivasalu, Deepak Balasubramanian, Pushpaja KU, Anoop Ramesan Nair, Chelakkot G Prameela, Krishnakumar Thankappan, Subramania Iyer. Radical radiotherapy for carcinoma of the larynx in the elderly: Functional and oncological outcomes from a tertiary cancer care centre in India. Indian Journal of Cancer 2017; 54:493-497
13. Durga Menon and Prameela G Chelakkot. Reirradiation for recurrent primary central nervous system tumours: Eight-year audit from a tertiary cancer care centre in south India. Indian Journal of Cancer.2017;54:409-414 (http://www.indianjcancer.com/text.asp?2017/54/2/409/225792)
14. Prameela G Chelakkot, Ravind, Rahul, K, Sruthi et al. Adjuvant hypofractionated radiation in carcinoma breast – Photon versus Electron: Comparison of treatment outcome. Journal of Cancer Research and Therapeutics. 2017;13(2):262-267 (DOI: 10.4103/0973-1482.192851)
15. Prameela G Chelakkot, Ravind, Rahul. Leiomyosarcoma of scrotum: A rare in-field second malignancy in a previously irradiated carcinoma of prostate and review of literature. Journal of Cancer Research and Therapeutics.2017;13:276-278 (DOI: 10.4103/0973-1482.189401)
16. Prameela G Chelakkot, Rahul Ravind, Renilmon, Sheejamol V S, Dinesh Makuny. 'Radiation dose to dysphagia aspiration related structures (DARS) and its effect on swallowing: Comparison of 3DCRT and IMRT plans. Journal of Cancer Research and Therapeutics. 2016; 12:845-51 (DOI: 10.4103/0973-1482.163676)
17. Rahul Ravind, Prameela G Chelakkot, Bharath Chandra Gurram, Makuny Dinesh. Synchronous phalangeal metastases in upper and lower limbs from primary breast malignancy: a rare case scenario with a review of the literature. BMJ Case Reports 2015. (DOI.10.1136/bcr-2015-213246)
18. Rahul Ravind, Prameela G Chelakkot, Bharath Chandra Gurram, Makuny Dinesh. Naughty knot: a case of nasogastric tube knotting. BMJ Case Reports. 2015. (DOI:10.1136/bcr-2015-209937)
19. Prameela G Chelakkot, Rahul Ravind, Bharath C Gurram, Sheejamol V S, Makuny Dinesh. “Prognostic factors in primary vaginal cancer: A single institute experience and review of literature”. Journal of Obstetrics and Gynecology of India.2016; 66, (5)363-371
20. Prameela G Chelakkot, Rahul Ravind, P Md Zaheeruddin, Wesley M Jose, Sheejamol V S, M Dinesh. “Hyponatremia: Is there an association with disease profile in head and neck malignancies? Audit from a tertiary cancer care centre”. GIPMER Journal of Cancer.
21. Zaheeruddin PM, Prameela CG, Antony MA, Pavithran K, Dinesh M. Metastatic endometrial carcinoma in the lung: unusual timing and site. South African Journal of Gynaecologic Oncology 2013; 5 (2): 64-67

ABSTRACTS PUBLISHED

1. V. Srinivasalu, Narayana Subramaniam, Narender Kumar, D. Balasubramaniam, A. Philip, Prameela Govindalayathil Chelakkot, Anoop Ramesan Nair, A Susan, Pushpaja Ullattil, Krishnakumar Thankappan, Wesley M Jose, Subramania Iyer, Keechilat Pavithran. Do patients over 70 years with advanced head and neck squamous cell carcinoma tolerate curative intent concurrent chemo-radiation? Predictors of oncological outcomes. Annals of Oncology 28 (supplement 5), 2017 (doi:10.1093/annonc/mdx374.033)
2. S. Sashidharan, C Prasad, A Ramesan Nair, Prameela Govindalayathil Chelakkot. Outcomes of p16 positive oropharyngeal squamous cell carcinoma treated with radiotherapy – Results from a tertiary care center in South India. Annals of Oncology 27 (supplement 9), 2016. (doi:10.1093/annonc/mdw587.020)
3. Chelakkot G. Prameela, R. Anoop, K. Sruthi, Rahul Ravind. Re-irradiation in head and neck malignancies: Challenges and outcomes. Journal of Cancer Research and Therapeutics. 2016
4. Chelakkot G. Prameela, Rahul Ravind, Smitha N Vijayan, Sruthi K, Sheejamol V S, K Pavithran. Triple negative breast cancer and androgen receptor expression: a forerunner for a novel hormonal approach. Annals of Oncology. 26 (Supplement 9) ix 153 – ix 155, 2015 (doi:10.1093/annonc/mdv534.1)
5. Prameela C G, R Ravind, M Dinesh. Significance of patterns of failure after treatment with curative intent in adenocarcinoma of stomach. European Journal of Cancer. 07/2015; 51(2)
6. R Ravind, C G Prameela, M Dinesh. Subventricular zone irradiation in glioblastoma: can it increase survival? European Journal of Cancer 07/2015; 51(2)
7. Chelakkot G Prameela, Rahul Ravind, P Md Zaheeruddin. Hyponatremia: Is there an association with disease profile in head and neck malignancies? Audit from a tertiary cancer care centre. Journal of Cancer Research and Therapeutics. Supplement 1-2014. Vol 10. S3
8. Chigurupati Namrata, Rahul Ravind, Surya Prakash Vankina, Chelakkot G Prameela. Dysphagia following total glossectomy and adjuvant chemoradiation in a recurrent malignancy of tongue: cure versus quality of life? Journal of Cancer Research and Therapeutics. 01/2014; 10(6):17-72.
9. Chelakkot G Prameela, Smitha N Vijayan, Rahul Ravind, Sheejamol V S, Keechilat Pavitran. Triple negative breast cancer: is androgen receptor expression a promising target? Journal of Cancer Research and Therapeutics. Supplement 1-2014. Vol 10. S29
10. Govindalayathil Prameela C, Vijayan N, Ravind R, Sheejamol V S, Keechilat P. Androgen receptor expression in triple negative breast cancer. International Journal of Gynecological Cancer 05/2014; 24:12-13
11. Chelakkot G Prameela, Rahul Ravind, Haridas M Nair, Renilmon P S, Sheejamol V S, Makuny Dinesh. Dose to Dysphagia Aspiration Related Structures (DARS) and its effect on swallowing: Comparison of 3DCRT vs IMRT plans. European Journal of Cancer. Vol 50, Supplement 4. May 2014, e38-e39
12. Prameela G Chelakkot, Vijayan N, Rahul Ravind, Sheejamaol V S, Keechilat Paithran. Androgen receptor expression in Triple negative breast cancer. European Journal of Cancer. 03/2014; 50: S196
13. Prameela G Chelakkot, Rahul Ravind, Makuny Dinesh. Adjuvant hypofractionated radiation to breast: photon versus electron: Results from a tertiary cancer care centre. European Journal of Cancer 03/2014; Vol. 50: S216
14. Zaheeruddin PM, Prameela C G, Dinesh M. Impact of intraluminal brachytherapy in the treatment of carcinoma oesophagus: Experience from a tertiary cancer care centre. Indian Journal of Cancer 11/2013; 50(Supplement 1): S259.
15. Gurram BC, Arunlal M, Prameela C G, Ravind R, Pavithran K, Dinesh M. Tri-modality treatment in resectable oesophageal carcinoma: Is this the way to go? Indian Journal of Cancer 11/2013; 50(Supplement 1)
16. Antony MA, Prameela C G, Vijayakumar DK. Vulval cancer: Patterns of failure from a tertiary care centre. Indian Journal of Cancer 11/2013; 50(Supplement 1).
17. Antony MA, Prameela C G, Kiran, Vijayakumar DK, Pavithran K. Management of Granulosa cell tumour of Ovary. Indian Journal of Cancer 10/2013; 50(Supplement 1): S108
18. Chelakkot G Prameela, Rahul Ravind, Makuny Dinesh. Adjuvant hypofractionated radiation to breast: Photon versus Electron: Results from a tertiary cancer care centre. European breast cancer congress – EBCC 9 – (Abstract no 557)
19. Chelakkot G Prameela, Smitha N Vijayan, Rahul Ravind, Sheejamol V S, Keechilat Pavithran. Androgen receptor expression in triple negative breast cancer. European breast cancer congress – EBCC 9 – (Abstract no 495).
20. Chelakkot G Prameela, Rahul Ravind, Makuny Dinesh. Hypofractionated radiation to breast: Photon versus Electron: Results from a tertiary cancer care centre. KBCCC2014 (Kyoto Breast Cancer Conference - 2014 - Page No: 59).

Book Chapters published:

1. Dr Prameela Chelakkot - Swallowing dysfunction after radiotherapy and chemotherapy in head and neck cancers. Dysphagia Management in Head and Neck Cancers. A Manual and Atlas. Springer Publication. Editors: Thankappan, Krishnakumar, Iyer, Subramania, Menon, Jayakumar R (Eds.) ISBN 978-981-10-8282-5. 2018
2. Prameela CG - Guidelines in the Management of Oropharyngeal Cancer. Basic Concepts in head & Neck Surgery and oncology. The Health Sciences Publishers, New Delhi. 2015. Chapter 23. pages 145 – 157
3. Chelakkot G Prameela - Vaginal Malignancies. Handbook of Gynecologic Oncology - 2015. Published by Department of Oncology, Amrita Institute of Medical Sciences, Kochi. Kerala.

InternatioNal Conferences since 2008

1. ESMO-Asia 2016, Held at Singapore. From 16th December to 19th December, and presented a poster.
2. AOS 2015, 11th OOTR Annual Conference, Viral Hepatitis 2015 Held at Shanghai, China, from 10th – 12th April, 2015 and presented a poster.
3. Asian Oncology Summit & Organisation Oncology Translational Research (AOS – OOTR) 2014, at Kuala Lumpur. Apr 11th to 13th, 2014.
4. Kyoto Breast Cancer Consensus Conference – KBCCC 2014, Kyoto, Japan. Feb 20th to 22nd - 2014.
5. OOTR 8th Annual Conference (Organisation Oncology Translational Research) Conference, at Kyoto, Japan. April 20th, 21st – 2012.
6. Kyoto Breast Cancer Consensus Conference, Kyoto, Japan. April 14th – 16th – 2011.
7. Breast Cancer Consensus at San Antonio, Texas, USA. December 2009.
8. The Asia Pacific Expert Meet, in association with The Global Breast Cancer Conference 2009 and the 7th Biennial Meeting of the Asian Breast Cancer Society. Seoul, South Korea. 7th to 10th October, 2009.
9. Early Breast cancer consensus at St Galen, Switzerland. March 2009.
10. European Association of Lung Cancer conference at Turin, Italy. March 2008.
11. International Radiology and Oncology conference at Singapore. January 2008

Educational Qualification

Referrences

Prof. M.S.Vidyasagar, Professor, Head and Director, Department of Radiotherapy and Oncology, Father Muller’s Medical College and Research Centre, Mangalore, Karnataka, India.

Prof. K. Koteshwar Rao, Dean, Mamta medical College, Kammam. Hyderabad.